All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule arrays such as the mitotic spindle.Cargo-specific adaptors engage with dynein to recruit and activate the motor, but the molecular mechanisms remain incompletely understood.Here, we use struc
Objectives: Patient-reported outcomes gain importance for the assessment of auditory abilities in cochlear implant users and for the evaluation of auditory rehabilitation.Aims of the study were to explore the interrelation of self-reported improvements in auditory ability with improvements in speech comprehension and to identify factors other than
Background: An herbal galactagogue formula in Thai traditional medicine, known as the Prasanamnom formula (PNF), has been utilized to increase maternal breast milk.The traditional method read more of administering PNF is via decoction, which has become inconvenient in modern times.Consequently, it has been newly produced in a powdered form for caps
Mammography has undergone significant improvement as screening tool for early diagnosis of breast cancer as a means of reducing mortality rate in them.The quality of mammograms and interpretative skills of the radiologist are important determinants required to achieve the favourable mortality reduction rates that have been established in randomised
The progression of calcific aortic valve disease (CAVD) is characterized by extracellular matrix (ECM) remodeling, leading to structural abnormalities and improper valve function.The focus of the present study was to relate aortic valve leaflet axial curvature changes as a function of elastin degradation, which has been associated with CAVD.Circumf